Migraine Drug May Increase Risk of Kidney Stones
Topomax, a medication frequently prescribed for migraine headaches as well as weight loss, may up the risk of kidney stones. In a study published by the National Kidney Foundation, researchers found that the drug appeared to deplete citrate in the urine of patients, an ion that helps inhibit the calcium salt crystallization that can develop into some types of kidney stones. The study included 12 patients who were prescribed Topomax by providers in a headache clinic. A 24-hour urine sample was collected before beginning the medication, and again 30 days and 60 days after starting the drug. On average, the patients' urinary citrate excretion decreased to 279 mg per day after being on Topomax for 30 days.
Read More
